As the paragraph descriping shows that 5676-60-8 is playing an increasingly important role.
With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.5676-60-8,2-Methylbenzo[d]oxazol-6-amine,as a common compound, the synthetic route is as follows.,5676-60-8
INTERMEDIATE B2 7V-(4-Bromo-2-hydroxyphenyl)acetamide – -To a cooled (0 0C) suspension of 2-methyl-l,3-benzoxazol-6-amine (Intermediate Bl; 1.96 g, 13.2 mmol) in 1 M HBr (40 niL) was carefully added NaNO2 (1.38 g, 20 mmol). After stirring for 10 min, a solution of CuBr (2.92 g, 20 mmol) in water (14 mL) was added and the mixture was stirred at 0 0C for 5 min. The ice-bath was removed and the mixture was stirred overnight and then 25% aqueous ammonia (5 mL) was added. The mixture was extracted with EtOAc (500 mL) and the organic layer was concentrated. The residue was purified by flash chromatography on silica using MeOH/CHCl3 (0.05:1) as eluent. Yield 1.47 g (32%). Analytical HPLC: purity 100% (System A); LRESIMS (ESI+) m/z = 230/232 (M+H)+.
As the paragraph descriping shows that 5676-60-8 is playing an increasingly important role.
Reference£º
Patent; INOVACIA AB; WO2009/150144; (2009); A1;,
Benzoxazole – Wikipedia
Benzoxazole | C7H5NO – PubChem