N-Acylbenzotriazole as Efficient Ligand in Copper-Catalyzed O-Arylation Leading to Diverse Benzoxazoles was written by Singh, Anoop S.;Singh, Mala;Mishra, Nidhi;Mishra, Snigdha;Agrahari, Anand K.;Tiwari, Vinod K.. And the article was included in ChemistrySelect in 2017.Category: benzoxazole This article mentions the following:
An establishment of (1H-benzo[d][1,2,3]triazol-1-yl)(2-methoxyphenyl)methanone as ligand was attained in intramol. C-O cross-coupling of N-(2-halophenyl)aryl/alkylamide derivatives XC6H4NHC(O)R [R = (CH2)10CH3, C6H5, 2-H3CC6H4, etc.; X = 2-Cl, 2-Br, 2,6-Cl2-4-Br] to form 2-aryl/alkyl benzoxazole derivatives I (Y = H, 4-Cl-6-Br) using CuI/K2CO3 as catalytic system. Salient advantages associated with this pathway include easily available starting materials, cheap catalyst, highly stable ligand, wide substrate scope, smooth reaction, easy work-up and high product yield. In the experiment, the researchers used many compounds, for example, 2-(3-Bromophenyl)benzo[d]oxazole (cas: 99586-31-9Category: benzoxazole).
2-(3-Bromophenyl)benzo[d]oxazole (cas: 99586-31-9) belongs to benzoxazole derivatives. Benzoxazoles belong to the group of well-known antifungal agents with antioxidant, antiallergic, antitumoral and antiparasitic activity. The wide range in therapeutic potential of benzoxazole derivatives is related to the favourable interactions of the benzoxazole moiety with different protein targets.Category: benzoxazole
Referemce:
Benzoxazole – Wikipedia,
Benzoxazole | C7H5NO – PubChem