Some tips on 151230-42-1

With the complex challenges of chemical substances, we look forward to future research findings about 6-Bromo-2-methylbenzo[d]oxazole

It is a common heterocyclic compound, the benzoxazole compound, 6-Bromo-2-methylbenzo[d]oxazole, cas is 151230-42-1 its synthesis route is as follows.,151230-42-1

A mixture of 114-1 (1.00 g, 4.72 mmol), NBS (840 mg, 4.72 mmol), and AIBN (350 mg) in CCl4 (20 mL) is heated at 90 C for 16 h. The reaction is cooled to ambient temperature, diluted with DCM (100 mL), washed with H2O (2 x 75 mL), dried over Na2SO4, filtered and concentrated. The residue is purified by flash chromatography (0- 50% EtOAc in heptane) to give 114-2.

With the complex challenges of chemical substances, we look forward to future research findings about 6-Bromo-2-methylbenzo[d]oxazole

Reference£º
Patent; BOEHRINGER INGELHEIM INTERNATIONAL GMBH; ABEYWARDANE, Asitha; BRUNETTE, Steven Richard; BURKE, Michael Jason; KIRRANE, Thomas Martin, Jr.; MAN, Chuk Chui; MARSHALL, Daniel Richard; PADYANA, Anil Kumar; RAZAVI, Hossein; SIBLEY, Robert; SMITH KEENAN, Lana Louise; SNOW, Roger John; SORCEK, Ronald John; TAKAHASHI, Hidenori; TAYLOR, Steven John; TURNER, Michael Robert; YOUNG, Erick Richard Roush; ZHANG, Qiang; ZHANG, Yunlong; ZINDELL, Renee M.; WO2014/14874; (2014); A1;,
Benzoxazole – Wikipedia
Benzoxazole | C7H5NO – PubChem