Some tips on 177492-52-3

177492-52-3, In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles.,177492-52-3 ,Benzo[d]oxazol-6-amine, other downstream synthetic routes, hurry up and to see

As a common heterocyclic compound, it belongs to benzoxazole compound, name is Benzo[d]oxazol-6-amine, and cas is 177492-52-3, its synthesis route is as follows.

General procedure: HBTU (147 mg, 0.39 mmol) and DIPEA (0.13 g, 1.0 mmol) were added to a solution of 4-(quinolin-2-ylmethoxy)benzoic acid (100 mg, 0.35 mmol) in DMF (5 mL), and the mixture was stirred at room temperature for 30 min N-methylaniline (38 mg, 0.35 mmol) was added, and the resulting mixture was stirred at room temperature for 12 h. Water (15 mL) was added, the resultant mixture was extracted with EtOAc (15 mL). The organic layer was separated, dried over Na2SO4, filtered, and concentrated under vacuum. The residue was purified by preparative HPLC to afford the title compound as an off white solid (11% yield).

177492-52-3, In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles.,177492-52-3 ,Benzo[d]oxazol-6-amine, other downstream synthetic routes, hurry up and to see

Reference:
Article; Kilburn, John Paul; Kehler, Jan; Langgard, Morten; Erichsen, Mette N.; Leth-Petersen, Sebastian; Larsen, Mogens; Christoffersen, Claus Tornby; Nielsen, Jacob; Bioorganic and Medicinal Chemistry; vol. 21; 19; (2013); p. 6053 – 6062;,
Benzoxazole – Wikipedia
Benzoxazole | C7H5NO – PubChem