New discoveries in chemical research and development in 2021. The transformation of simple hydrocarbons into more complex and valuable products has revolutionised modern synthetic chemistry. In an article, author is Yang, Xiaofeng, once mentioned the application of 405-50-5, Name: 2-(4-Fluorophenyl)acetic acid, Name is 2-(4-Fluorophenyl)acetic acid, molecular formula is C8H7FO2, molecular weight is 154.14, category is benzoxazole. Now introduce a scientific discovery about this category.
A ratiometric fluorescence pH probe 1 based on through-bond energy transfer (TBET) with a 2-(2-hydroxyphenyl)benzoxazole (HBO) as donor and a Rhodamine derivative as acceptor is developed through simple condensation reaction. The probe exhibits a ratiometric fluorescence emission (I-593/I-422) characteristics and linear response to extreme acidity range of 5.00-2.88, and a ratiometric fluorescence emission (I-555/I-422) characteristics and linear response to extreme alkaline range of 10.00-13.78, respectively. Moreover, 1 possesses highly selective response to pH over metal ions, good reversibility and excellent photostability. Probe 1 is cellpermeable and can distinguish near pH 5.55 fluctuations in Hela cells. Furthermore, 1 can be immobilized on a test paper, which shows a rapid and reversible colorimetric response to HCl/NH3 vapor by the naked-eye.
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Reference:
Benzoxazole – Wikipedia,
,Benzoxazole | C7H5NO – PubChem