Tag: 100-200

Electronic and vibrational spectra of 2-chloro-and 2,5-dimethyl benzothiazole and 2,5-dimethyl benzoxazole was written by Agrawal, Saumya;Srivastava, R. L.;Shukla, M. M.. And the article was included in Acta Ciencia Indica, Physics in 1993.Related Products of 5676-58-4 This article mentions the following:

This paper contains the anal. and assignment of electronic absorption spectra of 2-chloro- and 2,5-di-Me benzothiazole and 2,5-di-Me benzoxazole in liquid and vapor state in the region 50000-28000 cm^-1 together with their IR absorption spectra in the region 40000-400 cm^-1. In the experiment, the researchers used many compounds, for example, 2,5-Dimethylbenzoxazole (cas: 5676-58-4Related Products of 5676-58-4).

2,5-Dimethylbenzoxazole (cas: 5676-58-4) belongs to benzoxazole derivatives. Its aromaticity makes it relatively stable, although as a heterocycle, it has reactive sites which allow for functionalization. Benzoxazoles are prominent in medicinal chemistry due to their wide spectrum of pharmacological activities such as anti-inflammatory, antimycobacterial, antihistamine.Related Products of 5676-58-4

Referemce:
Benzoxazole – Wikipedia,
Benzoxazole | C7H5NO – PubChem

A Green and Efficient Protocol for the Synthesis of Quinoxaline, Benzoxazole and Benzimidazole Derivatives Using Heteropolyanion-Based Ionic Liquids: As a Recyclable Solid Catalyst was written by Vahdat, Seyed Mohammad;Baghery, Saeed. And the article was included in Combinatorial Chemistry & High Throughput Screening in 2013.Application In Synthesis of 2,5-Dimethylbenzoxazole This article mentions the following:

In this paper, the authors introduce two non-conventional ionic liquid compounds which are composed of propane sulfonate functionalized organic cations and heteropoly anions as green solid acid catalysts for the highly efficient and green synthesis of 2,3-disubstituted quinoxaline derivatives These ionic liquids are in the solid state at room temperature and the synthesis is carried out by a one-pot condensation reaction of various phenylenediamine derivatives with 1,2-diketone derivatives Benzoxazole and benzimidazole derivatives were also synthesized by these novel catalysts by a one-pot condensation from reaction orthoester with o-aminophenol (synthesis of benzoxazole derivatives) and phenylenediamine (synthesis of benzimidazole derivatives). All experiments successfully resulted in the desired products. The described novel synthesis method has several advantages of easy handling of reactants, mild reaction conditions, high yields, short reaction times, simplicity and easy workup compared to the traditional method of synthesis. The synthesis of the target compounds was achieved using as catalysts 1-methyl-3-(3-sulfopropyl)-1H-imidazolium tetracosa-μ-oxododecaoxo[μ₁₂-[phosphato(3-)-κO:κO:κO:κO‘:κO‘:κO‘:κO”:κO”:κO”:κO”’:κO”’:κO”’]]dodecatungstate(3-) (3:1) [1-methyl-3-(3-sulfopropyl)-1H-imidazolium tungstophosphate [PW₁₂O₄₀^3-]] and N,N,N-triethyl-3-sulfo-1-propanaminium tetracosa-μ-oxododecaoxo[μ₁₂-[phosphato(3-)-κO:κO:κO:κO‘:κO‘:κO‘:κO”:κO”:κO”:κO”’:κO”’:κO”’]]dodecatungstate(3-) (3:1) [1-methyl-3-sulfo-1-propanaminium tungstophosphate [PW₁₂O₄₀^3-]] as catalysts. The title compounds thus formed included 2,3-diphenylquinoxaline derivatives, 1H-benzimidazole derivatives, benzoxazole derivatives, dibenzo[a,c]phenazine, acenaphtho[1,2-b]quinoxaline, 2,5-dimethylbenzoxazole. In the experiment, the researchers used many compounds, for example, 2,5-Dimethylbenzoxazole (cas: 5676-58-4Application In Synthesis of 2,5-Dimethylbenzoxazole).

2,5-Dimethylbenzoxazole (cas: 5676-58-4) belongs to benzoxazole derivatives. Its aromaticity makes it relatively stable, although as a heterocycle, it has reactive sites which allow for functionalization. It is found within the chemical structures of pharmaceutical drugs such as flunoxaprofen and tafamidis.Application In Synthesis of 2,5-Dimethylbenzoxazole

Referemce:
Benzoxazole – Wikipedia,
Benzoxazole | C7H5NO – PubChem

Simple and efficient one-pot synthesis of 2-substituted benzoxazole and benzothiazole was written by Patil, Sachin S.;Bobade, Vivek D.. And the article was included in Synthetic Communications in 2010.Name: 2,5-Dimethylbenzoxazole This article mentions the following:

2-Substituted benzoxazole and benzothiazole were synthesized from condensation of aldehyde and 2-aminophenol or 2-aminothiophenol via a one-pot process using di-Et bromophoshonate and tert-Bu hypochlorite. In the experiment, the researchers used many compounds, for example, 2,5-Dimethylbenzoxazole (cas: 5676-58-4Name: 2,5-Dimethylbenzoxazole).

2,5-Dimethylbenzoxazole (cas: 5676-58-4) belongs to benzoxazole derivatives. Benzoxazole nucleus is one of the most important heterocyclic compounds exhibiting remarkable pharmacological activities. Due to its versatile biological properties, benzoxazole has been incorporated as an essential pharmacophore and substructure in many medicinal compounds.Name: 2,5-Dimethylbenzoxazole

Referemce:
Benzoxazole – Wikipedia,
Benzoxazole | C7H5NO – PubChem

Infrared behavior of heterocycles (bases for photographic sensitizers) according to the nature of the heteroatom and the substituents was written by Bassignana, P.;Cogrossi, C.;Gandino, M.. And the article was included in Chimie et Industrie (Paris) in 1963.Electric Literature of C9H9NO This article mentions the following:

A number of instances are given in which IR frequency shifts of the out-of-plane CH deformation of a 5-membered heterocyclic ring can be correlated with the electronegativity of the heteroatom. The successive introduction of functional groups R, electron donors and acceptors, into position 5 or 6 in the aromatic ring produces out-of-plane vibration displacements of the CH adjacent to the substituted C. A decrease of ν of the nearby CH groups corresponds to a decrease of electronegativity of the heteroatom. This is true of benzo- and 2-methylbenzo derivatives Changes occur when a 2nd heteroatom is introduced in a β position to that of the 1st hetero-atoms (oxazole, thiazole, selenazole). The vibrations then are influenced by the 2 heteroatoms. In keeping the same heteroatom (N) in the 3-position in the heterocyclic nucleus, and in changing the heteroatom in position 1, it is not possible to trace a straight line on a plot of frequency vs. electronegativity according to the Pauling electronegativity series. In effect, a broken line occurs, to which corresponds the min. value of the frequency of out-of-plane CH deformation when the 2nd heteroatom is N. An increase in CH frequency deformation with a decrease in-electronegativity is established (except when the 2nd heteroatom is N). In the experiment, the researchers used many compounds, for example, 2,5-Dimethylbenzoxazole (cas: 5676-58-4Electric Literature of C9H9NO).

2,5-Dimethylbenzoxazole (cas: 5676-58-4) belongs to benzoxazole derivatives. Benzoxazole derivatives have different biological activities. Due to its versatile biological properties, benzoxazole has been incorporated as an essential pharmacophore and substructure in many medicinal compounds.Electric Literature of C9H9NO

Referemce:
Benzoxazole – Wikipedia,
Benzoxazole | C7H5NO – PubChem

Nano CeO2 as a new green and recyclable catalyst for the synthesis of 2-aryl Benzoxazole was written by Baghernejad, Bita;Samaie, Reyhaneh. And the article was included in Asian Journal of Nanoscience and Materials in 2021.Category: benzoxazole This article mentions the following:

In this research, a simple method for the synthesis of high-efficiency 2-aryl benzoxazoles I [R¹ = H, Me, Cl; R² = H. Me, Cl] via reaction of aminophenols and aldehyde derivatives under solvent-free conditions in the presence of a catalytic amount of nano-CeO₂ was presented. Some of these derivatives I have anticoagulant, antispasmodic, diuretic, anti-cancer and anti-anaphylactin properties. The results revealed that this synthetic reaction was very simple and benzoxazole derivatives produced with good yields compared to other studies. Mild conditions, high speed and short reaction time, simplicity of product separation process, high efficiency and purity of synthesized derivatives were the advantages of the proposed method. Highest efficiency (95%) in a short time (15 min) was obtained in this study, which was very important compared to other previous methods presented. In the experiment, the researchers used many compounds, for example, 2,5-Dimethylbenzoxazole (cas: 5676-58-4Category: benzoxazole).

2,5-Dimethylbenzoxazole (cas: 5676-58-4) belongs to benzoxazole derivatives. Benzoxazoles belong to the group of well-known antifungal agents with antioxidant, antiallergic, antitumoral and antiparasitic activity. Benzoxazoles are prominent in medicinal chemistry due to their wide spectrum of pharmacological activities such as antibacterial, antifungal, anticancer.Category: benzoxazole

Referemce:
Benzoxazole – Wikipedia,
Benzoxazole | C7H5NO – PubChem

Silica supported fluoroboric acid: an efficient and reusable heterogeneous catalyst for facile synthesis of 2-aliphatic benzothiazoles, benzoxazoles, benzimidazoles and imidazo[4,5-b]pyridines was written by Patil, Abasaheb V.;Bandgar, Babasaheb P.;Lee, Soo-Hyoung. And the article was included in Bulletin of the Korean Chemical Society in 2010.Category: benzoxazole This article mentions the following:

2-Substituted benzothiazoles, benzoxazoles, benzimidazoles and imidazo[4,5-b]pyridines were prepared by cyclization of aminophenols, aminothiophenols, phenylenediamines and a pyridinediamine with ortho esters using silica-supported tetrafluoroboric acid a catalyst. In the experiment, the researchers used many compounds, for example, 2,5-Dimethylbenzoxazole (cas: 5676-58-4Category: benzoxazole).

2,5-Dimethylbenzoxazole (cas: 5676-58-4) belongs to benzoxazole derivatives. Benzoxazole nucleus is one of the most important heterocyclic compounds exhibiting remarkable pharmacological activities. In the past years, numerous benzoxazole derivatives have been synthesised and evaluated for their biological potential.Category: benzoxazole

Referemce:
Benzoxazole – Wikipedia,
Benzoxazole | C7H5NO – PubChem

Palladium-Catalyzed Regioselective C-H Bond Arylations of Benzoxazoles and Benzothiazoles at the C7 Position was written by Abdellaoui, Fatma;Youssef, Chiraz;Ben Ammar, Hamed;Roisnel, Thierry;Soule, Jean-Francois;Doucet, Henri. And the article was included in ACS Catalysis in 2016.Formula: C9H9NO This article mentions the following:

We report herein, a very simple catalytic system for the direct arylation of benzoxazole and benzothiazole derivatives at C7 position, namely, phosphine-free PdCl₂ associated with PivOK in NMP at 150°. (Thio)phenoxy chelation-assisted Pd-catalyzed C-H bond cleavage, from an opened intermediate, was proposed to explain this unique regioselectivity. This reaction allows the synthesis of 2-amino-6-arylphenols through the ring opening of the benzoxazole. In the experiment, the researchers used many compounds, for example, 2,5-Dimethylbenzoxazole (cas: 5676-58-4Formula: C9H9NO).

2,5-Dimethylbenzoxazole (cas: 5676-58-4) belongs to benzoxazole derivatives. Being a heterocyclic compound, benzoxazole finds use in research as a starting material for the synthesis of larger, usually bioactive structures. Benzoxazoles are prominent in medicinal chemistry due to their wide spectrum of pharmacological activities such as anti-inflammatory, antimycobacterial, antihistamine.Formula: C9H9NO

Referemce:
Benzoxazole – Wikipedia,
Benzoxazole | C7H5NO – PubChem

Cu-catalysed transamidation of unactivated aliphatic amides was written by Kumar, Vishal;Dhawan, Sanjeev;Bala, Renu;Mohite, Sachin Balaso;Singh, Parvesh;Karpoormath, Rajshekhar. And the article was included in Organic & Biomolecular Chemistry in 2022.COA of Formula: C9H9NO This article mentions the following:

Direct transamidation was gaining prominence as a ground-breaking technique that generates a wide variety of amides without the requirement of acid-amine coupling or other intermediate steps. However, transamidation of unactivated aliphatic amides, on the other hand, was a long-standing issue in comparison to transamidation of activated amides. Herein, a transamidation approach of an unactivated aliphatic amide using a copper catalyst and chlorotrimethylsilane as an additive was reprted. In addition, used transamidation as a tool for selective N-C(O) cleavage and O-C(O) formation to synthesize 2-substituted benzoxazoles and benzothiazoles. The reactions were carried out without using any solvents and offered wide substitution scope. In the experiment, the researchers used many compounds, for example, 2,5-Dimethylbenzoxazole (cas: 5676-58-4COA of Formula: C9H9NO).

2,5-Dimethylbenzoxazole (cas: 5676-58-4) belongs to benzoxazole derivatives. Benzoxazole derivatives have gained a lot of importance in the past few years because of their use in intermediates for the preparation of new biological materials. Benzoxazoles are prominent in medicinal chemistry due to their wide spectrum of pharmacological activities such as anti-inflammatory, antimycobacterial, antihistamine.COA of Formula: C9H9NO

Referemce:
Benzoxazole – Wikipedia,
Benzoxazole | C7H5NO – PubChem

Chemical composition and anti-inflammatory activity of the essential oil of Nigerian Psorospermum tenuifolium (Hook. F.) was written by Zubair, M. F.;Oladosu, I. A.;Olawore, N. O.;Fakunle, C. O.. And the article was included in International Journal of Essential Oil Therapeutics in 2009.Application In Synthesis of 2,5-Dimethylbenzoxazole This article mentions the following:

The chem. composition of the essential oils obtained by hydrodistillation from the leaves and roots of Psorospermum tenuifolium collected from North Central Nigeria were analyzed by GC and GC/MS. Twenty-nine compounds representing 93.54% of the leaf essential oil and thirteen compounds representing 83.63% of the root essential oil were determined The two types of oils were differentiated according to their main components. The major constituents of the leaf oil were linalool, α-terpineol,β-caryophyllene, 3-carene and α-gurjunene. The root oil was predominantly monoterpenes that included α-pinene, β-pinene, limonene and myrcene. The leaf essential oil was subjected to anti-inflammatory assay due to its higher number of compounds At 5.0 and 2.5 mg dose levels, the oil exhibited significant anti-inflammatory activity with an edema reduction of 92.3% and 76.9% resp., which was more effective than that demonstrated by a 0.25 mg dose of indomethacin. In the experiment, the researchers used many compounds, for example, 2,5-Dimethylbenzoxazole (cas: 5676-58-4Application In Synthesis of 2,5-Dimethylbenzoxazole).

2,5-Dimethylbenzoxazole (cas: 5676-58-4) belongs to benzoxazole derivatives. Benzoxazoles belong to the group of well-known antifungal agents with antioxidant, antiallergic, antitumoral and antiparasitic activity. In the past years, numerous benzoxazole derivatives have been synthesised and evaluated for their biological potential.Application In Synthesis of 2,5-Dimethylbenzoxazole

Referemce:
Benzoxazole – Wikipedia,
Benzoxazole | C7H5NO – PubChem

Nuclear magnetic resonance study of the benzoxazole derivatives was written by Okuda, Hisashi;Nagai, Makoto. And the article was included in Bulletin of the Chemical Society of Japan in 1967.HPLC of Formula: 5676-58-4 This article mentions the following:

The proton N.M.R. spectra of 2,5-dimethylbenzoxazole, 2,5,7-trimethylbenzoxazole, 2,5,6-trimethylbenzoxazole, 2 methyl-5-chlorobenzoxazole, and 2,4,5-trimethylbenzoxazole are recorded in CCl4 (or CDCl3) and in CF3COOH. In neutral solution, the chem. shifts are interpreted in terms of π-electronic charge ds., magnetic anisotropy of the O and N heteroatoms, and the elec. field effect. Protonation of the N heteroatom in acid solution shifts all of the protons to lower field. To account for the linear dependence of the chem. shifts, corrected for the elec. and anisotropy contributions, with calculated π-electron ds. a proportionality constant of 3.37 ppm./electron is needed. In the experiment, the researchers used many compounds, for example, 2,5-Dimethylbenzoxazole (cas: 5676-58-4HPLC of Formula: 5676-58-4).

2,5-Dimethylbenzoxazole (cas: 5676-58-4) belongs to benzoxazole derivatives. Its aromaticity makes it relatively stable, although as a heterocycle, it has reactive sites which allow for functionalization. In the past years, numerous benzoxazole derivatives have been synthesised and evaluated for their biological potential.HPLC of Formula: 5676-58-4

Referemce:
Benzoxazole – Wikipedia,
Benzoxazole | C7H5NO – PubChem