Tag: 100-200

Synthesis and reactions of 3,4-dihydro-2H-1,4-benzoxazine derivatives was written by Kotha, Sambasivarao;Bindra, Vandana;Kuki, Atsuo. And the article was included in Heterocycles in 1994.Electric Literature of C9H9NO This article mentions the following:

Several 3,4-dihydro-2H-1,4-benzoxazine derivatives, e.g., I (R = H, Me), were prepared from com. available benzoxazoles II by use of an efficient two step sequence. Thus, II were reduced to give ring opened aminophenols which were cyclized with BrCH₂CH₂Br to give I. Aryl functionalization reactions allowing access to further benzoxazine derivatives are also described. In the experiment, the researchers used many compounds, for example, 2,5-Dimethylbenzoxazole (cas: 5676-58-4Electric Literature of C9H9NO).

2,5-Dimethylbenzoxazole (cas: 5676-58-4) belongs to benzoxazole derivatives. Benzoxazole derivatives have different biological activities. Benzoxazoles are prominent in medicinal chemistry due to their wide spectrum of pharmacological activities such as anti-inflammatory, antimycobacterial, antihistamine.Electric Literature of C9H9NO

Referemce:
Benzoxazole – Wikipedia,
Benzoxazole | C7H5NO – PubChem

Benzimidazoles and benzoxazoles via the nucleophilic addition of anilines to nitroalkanes was written by Aksenov, Alexander V.;Smirnov, Alexander N.;Aksenov, Nicolai A.;Bijieva, Asiyat S.;Aksenova, Inna V.;Rubin, Michael. And the article was included in Organic & Biomolecular Chemistry in 2015.Computed Properties of C9H9NO This article mentions the following:

PPA-induced umpolung triggers efficient nucleophilic addition of unactivated anilines to nitroalkanes to produce N-hydroxyimidamides. The latter undergo sequential acid-promoted cyclocondensation with ortho-hydroxy or ortho-amino moieties to afford benzoxazoles and benzimidazoles, e.g., I, resp. In the experiment, the researchers used many compounds, for example, 2,5-Dimethylbenzoxazole (cas: 5676-58-4Computed Properties of C9H9NO).

2,5-Dimethylbenzoxazole (cas: 5676-58-4) belongs to benzoxazole derivatives. Being a heterocyclic compound, benzoxazole finds use in research as a starting material for the synthesis of larger, usually bioactive structures. Benzoxazoles are prominent in medicinal chemistry due to their wide spectrum of pharmacological activities such as anti-inflammatory, antimycobacterial, antihistamine.Computed Properties of C9H9NO

Referemce:
Benzoxazole – Wikipedia,
Benzoxazole | C7H5NO – PubChem

Tungstate sulfuric acid as an efficient catalyst for the synthesis of benzoxazoles and benzothiazoles under solvent-free conditions was written by Farahi, Mahnaz;Karami, Bahador;Azari, Masume. And the article was included in Comptes Rendus Chimie in 2013.Formula: C9H9NO This article mentions the following:

Tungstate sulfuric acid (TSA) was found to be an efficient and reusable catalyst for the synthesis of benzoxazole and benzothiazole derivatives via reactions of ortho esters with o-aminophenols or o-aminothiophenols in high yields. In the experiment, the researchers used many compounds, for example, 2,5-Dimethylbenzoxazole (cas: 5676-58-4Formula: C9H9NO).

2,5-Dimethylbenzoxazole (cas: 5676-58-4) belongs to benzoxazole derivatives. Benzoxazole nucleus is one of the most important heterocyclic compounds exhibiting remarkable pharmacological activities. Due to its versatile biological properties, benzoxazole has been incorporated as an essential pharmacophore and substructure in many medicinal compounds.Formula: C9H9NO

Referemce:
Benzoxazole – Wikipedia,
Benzoxazole | C7H5NO – PubChem

Studies on the synthesis and photochemical properties of chain linked bisheteroarylethenes was written by Zhang, Wen-Qin;Wang, Shu-Li;Zhao, Hai-Tao;Zhuang, Jun-Peng;Sun, Hao;Zhao, Shu-Na;Zheng, Yan;Li, Chun-Bao. And the article was included in Gaodeng Xuexiao Huaxue Xuebao in 2000.Quality Control of 2,5-Dimethylbenzoxazole This article mentions the following:

1,3-Bis[trans-4-[2-[2-(5-methylbenzoxazolyl)]ethenyl]phenoxy]propane, 1,4-Bis[trans-4-[2-[2-(5-methylbenzoxazolyl)]ethenyl]phenoxy]butane, 1,6-Bis[trans-4-[2-[2-(5-methylbenzoxazolyl)]ethenyl]phenoxy]hexane, and 2,2′-bis[trans-4-[2-[2-(5-methylbenzoxazolyl)]ethenyl]phenoxy]ethyl ether were synthesized. Their structures were identified by elemental anal., IR, UV, ¹H NMR, ¹³C NMR and MS. The UV spectra were used to illustrate the change of title compounds under the irradiation of high-pressure-mercury-lamp. It was found that these compounds undergo two kinds of reactions, the trans-cis isomerization and intramol. photodimerization. The former is fast and reversible, and the latter is slow and irreversible. The speed of intramol. photodimerization will increase with increasing the length of the carbon chain between the two 2-[[2-(5-methylbenzoxazolyl)]ethenyl]phenyl group. The fact that the photodimerization is not affected by oxygen shows that the reaction proceeds through an excited singlet state. It is also revealed that title compounds undergo [2+2] photolysis easily when irradiated under short UV light. That the intramol. photodimerization and photolysis of these compounds can repeat many times indicate that these compounds have a high photostability. In the experiment, the researchers used many compounds, for example, 2,5-Dimethylbenzoxazole (cas: 5676-58-4Quality Control of 2,5-Dimethylbenzoxazole).

2,5-Dimethylbenzoxazole (cas: 5676-58-4) belongs to benzoxazole derivatives. Its aromaticity makes it relatively stable, although as a heterocycle, it has reactive sites which allow for functionalization. A number of marketed drugs are available having benzoxazole as core active moiety like, nonsteroidal anti-inflammatory drug (NSAID)—flunoxaprofen, benoxaprofen, antibiotic—calcimycin.Quality Control of 2,5-Dimethylbenzoxazole

Referemce:
Benzoxazole – Wikipedia,
Benzoxazole | C7H5NO – PubChem

ZrOCl₂.8H₂O as an efficient, environmentally friendly and reusable catalyst for synthesis of benzoxazoles, benzothiazoles, benzimidazoles and oxazolo[4,5-b]pyridines under solvent-free conditions was written by Mohammadpoor-Baltork, Iraj;Khosropour, Ahmad Reza;Hojati, Seyedeh Fatemeh. And the article was included in Catalysis Communications in 2007.Electric Literature of C9H9NO This article mentions the following:

A new and efficient method for the preparation of benzoxazoles, benzothiazoles, benzimidazoles, and oxazolo[4,5-b]pyridines from reactions of orthoesters with o-substituted aminoaroms. and 2-amino-3-hydroxypyridine in the presence of catalytic amounts of the moisture stable, inexpensive ZrOCl₂.8H₂O under solvent-free conditions was presented. This new protocol had the advantages of easy availability, easy handling, stability, reusability and eco-friendly of the catalyst, high yields, very short reaction times, solvent-free reaction conditions, simple exptl. and work-up procedure. In the experiment, the researchers used many compounds, for example, 2,5-Dimethylbenzoxazole (cas: 5676-58-4Electric Literature of C9H9NO).

2,5-Dimethylbenzoxazole (cas: 5676-58-4) belongs to benzoxazole derivatives. Benzoxazoles belong to the group of well-known antifungal agents with antioxidant, antiallergic, antitumoral and antiparasitic activity. Benzoxazoles are prominent in medicinal chemistry due to their wide spectrum of pharmacological activities such as anti-inflammatory, antimycobacterial, antihistamine.Electric Literature of C9H9NO

Referemce:
Benzoxazole – Wikipedia,
Benzoxazole | C7H5NO – PubChem

Thermochemistry of 2-methylbenzoxazole and 2,5-dimethylbenzoxazole: an experimental and computational study was written by Silva, Ana L. R.;Cimas, Alvaro;Ribeiro da Silva, Maria D. M. C.. And the article was included in Structural Chemistry in 2013.Formula: C9H9NO This article mentions the following:

The standard (p^o = 0.1 MPa) molar energies of combustion of 2-methylbenzoxazole and 2,5-dimethylbenzoxazole were measured by static-bomb combustion calorimetry. The standard molar enthalpies of vaporization, at T = 298.15 K, were obtained from high-temperature Calvet microcalorimetry. The exptl. results enable the calculation of the standard molar enthalpies of formation in the gaseous state, at T = 298.15 K, for both compounds, with the results discussed in terms of structural and energetic contributions. The theor. estimated gas-phase enthalpies of formation were calculated from high-level ab initio MO calculations at the G3(MP2)//B3LYP level of theory. The computed values compare very well with the exptl. results obtained in this work and show that the 2,5-dimethylbenzoxazole is enthalpically the most stable compound Furthermore, this composite approach was also used to obtain information about the gas-phase basicities, proton and electron affinities, and adiabatic ionization enthalpies. In the experiment, the researchers used many compounds, for example, 2,5-Dimethylbenzoxazole (cas: 5676-58-4Formula: C9H9NO).

2,5-Dimethylbenzoxazole (cas: 5676-58-4) belongs to benzoxazole derivatives. Being a heterocyclic compound, benzoxazole finds use in research as a starting material for the synthesis of larger, usually bioactive structures. The wide range in therapeutic potential of benzoxazole derivatives is related to the favourable interactions of the benzoxazole moiety with different protein targets.Formula: C9H9NO

Referemce:
Benzoxazole – Wikipedia,
Benzoxazole | C7H5NO – PubChem

Metal free montmorillonite KSF clay catalyzed practical synthesis of benzoxazoles and benzothiazoles under aerobic conditions was written by Kummari, Vijaya Babu;Chiranjeevi, Kalavakuntla;Suman Kumar, Alleni;Aravind Kumar, Rathod;Yadav, Jhillu Singh. And the article was included in Synthetic Communications in 2019.Name: 2,5-Dimethylbenzoxazole This article mentions the following:

An efficient method for the synthesis of benzoxazoles and benzothiazoles I [R = Cl, Me, NO₂, t-Bu; R¹ = Me, Et, i-Pr; X = O, S] via montmorillonite KSF clay catalyzed condensation reaction of β-diketones and 2-aminophenols or 2-aminothiophenols resp. was reported. The efficiency of the reaction reflected from the wide substrate scope with electronic differentiation on aryls. The reaction was metal free and proceeded without the exclusion of air or moisture, and further the catalyst could be recycled up to 3-5 catalytic cycles. In the experiment, the researchers used many compounds, for example, 2,5-Dimethylbenzoxazole (cas: 5676-58-4Name: 2,5-Dimethylbenzoxazole).

2,5-Dimethylbenzoxazole (cas: 5676-58-4) belongs to benzoxazole derivatives. Although benzoxazole itself is of little practical value, many derivatives of benzoxazoles are commercially important. Benzoxazoles are prominent in medicinal chemistry due to their wide spectrum of pharmacological activities such as antiparkinson, inhibition of hepatitis C virus, 5-HT3 antagonistic effect.Name: 2,5-Dimethylbenzoxazole

Referemce:
Benzoxazole – Wikipedia,
Benzoxazole | C7H5NO – PubChem

1,3-Dibromo-5,5-dimethylhydantoin as an efficient homogeneous catalyst for synthesis of benzoxazoles, benzimidazoles, and oxazolo[4,5-b]pyridines was written by Hojati, Seyedeh Fatemeh;Maleki, Behrooz;Beykzadeh, Zahra. And the article was included in Monatshefte fuer Chemie in 2011.HPLC of Formula: 5676-58-4 This article mentions the following:

A simple and highly efficient method for synthesis of benzoxazoles, benzimidazoles, and oxazolo[4,5-b]pyridines was described. Condensation of orthoesters with o-substituted anilines or 2-amino-3-hydroxypyridine was performed in the presence of catalytic amounts of com. available, inexpensive, and moisture-stable 1,3-dibromo-5,5-dimethylhydantoin under solvent-free conditions. The corresponding heterocycles were obtained in good to excellent yields. The main advantages of the present procedure are mild reaction conditions, short reaction times, high yields of products, easy work-up, and absence of solvent. In the experiment, the researchers used many compounds, for example, 2,5-Dimethylbenzoxazole (cas: 5676-58-4HPLC of Formula: 5676-58-4).

2,5-Dimethylbenzoxazole (cas: 5676-58-4) belongs to benzoxazole derivatives. Benzoxazoles belong to the group of well-known antifungal agents with antioxidant, antiallergic, antitumoral and antiparasitic activity. The wide range in therapeutic potential of benzoxazole derivatives is related to the favourable interactions of the benzoxazole moiety with different protein targets.HPLC of Formula: 5676-58-4

Referemce:
Benzoxazole – Wikipedia,
Benzoxazole | C7H5NO – PubChem

Iron(III) complexes with benzoxazole derivatives was written by Pinna, Rosalba;Ponticelli, Gustavo;Aramu, Francesco;Delunas, Adriano;Maxia, Vera. And the article was included in Transition Metal Chemistry (Dordrecht, Netherlands) in 1988.Related Products of 5676-58-4 This article mentions the following:

FeL_nX₃·mH₂O (L = benzoxazole, 2-methylbenzoxazole, 2,5-dimethylbenzoxazole (2,5-diMebenzox); n = 2, 3, 4, 6; X = Cl, Br, NO₃ or ClO₄; m = 0, 1, 2, 5) were prepared and studied by chem. anal., magnetic moments, IR, electronic, Moessbauer spectra and molar conductivity values. The oxazoles are N_ring bonded and the complexes are hexacoordinate in the solid state with exception of 5-coordinate Fe(2,5-diMebenzox)₂Br₃. In the experiment, the researchers used many compounds, for example, 2,5-Dimethylbenzoxazole (cas: 5676-58-4Related Products of 5676-58-4).

2,5-Dimethylbenzoxazole (cas: 5676-58-4) belongs to benzoxazole derivatives. The benzoxazole moiety is widely found in various natural compounds, which are often found to be biologically active. A number of marketed drugs are available having benzoxazole as core active moiety like, nonsteroidal anti-inflammatory drug (NSAID)—flunoxaprofen, benoxaprofen, antibiotic—calcimycin.Related Products of 5676-58-4

Referemce:
Benzoxazole – Wikipedia,
Benzoxazole | C7H5NO – PubChem

Copper-Containing Polyoxometalate-Based Metal-Organic Frameworks as Heterogeneous Catalysts for the Synthesis of N-Heterocycles was written by Li, Ke;Liu, Yu-Feng;Lin, Xiao-Ling;Yang, Guo-Ping. And the article was included in Inorganic Chemistry in 2022.HPLC of Formula: 5676-58-4 This article mentions the following:

Three new polyoxometalate-based metal-organic frameworks (POMOFs) [Cu₄(μ₃-OH)₂(tba)₃(H₂O)₅(SiW₁₂O₄₀)_0.5](H₂SiW₁₂O₄₀)_0.5·2.5H₂O (CuSiW), [Cu₃(μ₃-OH)(tba)₃(Htba)(H₂O)₂(HPMo₁₂O₄₀)]·7H₂O (CuPMo), and [Cu₄(μ₃-OH)₂(tba)₃(H₂O)₃(PW₁₂O₄₀)_0.5]₂(PW₁₂O₄₀)·0.5H₂O (CuPW) were constructed using multinuclear copper clusters, 3-(4H-1,2,4-triazol-4-yl)benzoic acid (Htba), and Keggin polyoxometalates (POMs). Different POMs regulate the formation of different multinuclear copper clusters (“boat” tetranuclear clusters in CuSiW, trinuclear clusters in CuPMo, and “chair” tetranuclear clusters in CuPW) and different topol. structures of CuSiW, CuPMo, and CuPW (3-connected two-dimensional (2D) network for CuSiW, 4-connected 2D network for CuPMo, and (4,6)-connected three-dimensional network for CuPW). CuSiW, CuPMo, and CuPW as heterogeneous catalysts combine the high stability of MOFs in polar solvents and excellent catalytic activity of POMs and could be used for the synthesis of nitrogen-heterocycle compounds The condensation cyclization reactions of 2-aminophenols/benzenesulfonyl hydrazines with 1,3-diketones produce benzoazoles and pyrazoles in good to excellent yields under the catalysis of CuPMo. Moreover, the catalyst could be reused at least for 7 runs, and this protocol was suitable for gram-scale reactions. In the experiment, the researchers used many compounds, for example, 2,5-Dimethylbenzoxazole (cas: 5676-58-4HPLC of Formula: 5676-58-4).

2,5-Dimethylbenzoxazole (cas: 5676-58-4) belongs to benzoxazole derivatives. Benzoxazoles belong to the group of well-known antifungal agents with antioxidant, antiallergic, antitumoral and antiparasitic activity. Due to its versatile biological properties, benzoxazole has been incorporated as an essential pharmacophore and substructure in many medicinal compounds.HPLC of Formula: 5676-58-4

Referemce:
Benzoxazole – Wikipedia,
Benzoxazole | C7H5NO – PubChem