Tag: 200-300

Ligand-Free Copper-Catalyzed Synthesis of Substituted Benzimidazoles, 2-Aminobenzimidazoles, 2-Aminobenzothiazoles, and Benzoxazoles was written by Saha, Prasenjit;Ramana, Tamminana;Purkait, Nibadita;Ali, Ashif Md;Paul, Rajesh;Punniyamurthy, Tharmalingam. And the article was included in Journal of Organic Chemistry in 2009.COA of Formula: C13H8BrNO This article mentions the following:

The synthesis of substituted benzimidazoles, 2-aminobenzimidazoles, 2-aminobenzothiazoles, and benzoxazoles is described via intramol. cyclization of o-bromoaryl derivatives using copper(II) oxide nanoparticles in DMSO under air. E.g., cyclization of o-bromoaryl amidine I gave 95% benzimidazoles II. The procedure is exptl. simple, general, efficient, and free from addition of external chelating ligands. It is a heterogeneous process and the copper(II) oxide nanoparticles can be recovered and recycled without loss of activity. In the experiment, the researchers used many compounds, for example, 2-(3-Bromophenyl)benzo[d]oxazole (cas: 99586-31-9COA of Formula: C13H8BrNO).

2-(3-Bromophenyl)benzo[d]oxazole (cas: 99586-31-9) belongs to benzoxazole derivatives. Benzoxazole nucleus is one of the most important heterocyclic compounds exhibiting remarkable pharmacological activities. Due to its versatile biological properties, benzoxazole has been incorporated as an essential pharmacophore and substructure in many medicinal compounds.COA of Formula: C13H8BrNO

Referemce:
Benzoxazole – Wikipedia,
Benzoxazole | C7H5NO – PubChem

Palladium (II) Complex Supported on Magnetic Nanoparticles Modified with Phenanthroline: A Highly Active Reusable Nanocatalyst for the Synthesis of Benzoxazoles, Benzothiazoles and Cyanation of Aryl Halides was written by Cai, Yuan;Yuan, Hailong;Gao, Qiang;Wu, Lili;Xue, Lijun;Feng, Nengjie;Sun, Yuan. And the article was included in Catalysis Letters.Application of 99586-31-9 This article mentions the following:

A well dispersed magnetically separable palladium complex (MNPs-phenanthroline-Pd) has been synthesized via the immobilization of palladium (II) complex on the surface of silica-coated magnetic nanoparticles modified with phenanthroline ligand. The SEM and TEM images of MNPs-phenanthroline-Pd at different magnification show that the catalyst is formed of nanometer-sized particles. The MNPs-phenanthroline-Pd nanocomposite was found to be an efficient catalyst for the synthesis of benzoxazoles, benzothiazoles and cyanation of aryl halides. The high efficiency and the ability to be recovered and reused for at least up to seven consecutive runs are some superior properties of the catalyst. SEM images of reused catalyst confirmed that there was no significant change in the morphol. and dispersion of the particles. In the experiment, the researchers used many compounds, for example, 2-(3-Bromophenyl)benzo[d]oxazole (cas: 99586-31-9Application of 99586-31-9).

2-(3-Bromophenyl)benzo[d]oxazole (cas: 99586-31-9) belongs to benzoxazole derivatives. Benzoxazole derivatives have gained a lot of importance in the past few years because of their use in intermediates for the preparation of new biological materials. Benzoxazoles are prominent in medicinal chemistry due to their wide spectrum of pharmacological activities such as antibacterial, antifungal, anticancer.Application of 99586-31-9

Referemce:
Benzoxazole – Wikipedia,
Benzoxazole | C7H5NO – PubChem

Biochemical and Structural Evaluation of Highly Selective 2-Arylbenzoxazole-Based Transthyretin Amyloidogenesis Inhibitors was written by Johnson, Steven M.;Connelly, Stephen;Wilson, Ian A.;Kelly, Jeffery W.. And the article was included in Journal of Medicinal Chemistry in 2008.Application In Synthesis of 2-(3-Bromophenyl)benzo[d]oxazole This article mentions the following:

To develop potent transthyretin (TTR) amyloidogenesis inhibitors that also display high binding selectivity in blood, it proves useful to systematically optimize each of the three substructural elements that comprise a typical inhibitor: the two aryl rings and the linker joining them. In the first study, described herein, structural modifications to one aryl ring were evaluated by screening a library of 2-arylbenzoxazoles bearing thyroid hormone-like aryl substituents on the 2-aryl ring. Several potent and highly selective amyloidogenesis inhibitors were identified that exhibit minimal thyroid hormone nuclear receptor and COX-1 binding. High resolution crystal structures (1.3-1.5 A) of three inhibitors (I, II, and III) in complex with TTR were obtained to characterize their binding orientation. Collectively, the results demonstrate that thyroid hormone-like substitution patterns on one aryl ring lead to potent and highly selective TTR amyloidogenesis inhibitors that lack undesirable thyroid hormone receptor or COX-1 binding. In the experiment, the researchers used many compounds, for example, 2-(3-Bromophenyl)benzo[d]oxazole (cas: 99586-31-9Application In Synthesis of 2-(3-Bromophenyl)benzo[d]oxazole).

2-(3-Bromophenyl)benzo[d]oxazole (cas: 99586-31-9) belongs to benzoxazole derivatives. The benzoxazole moiety is widely found in various natural compounds, which are often found to be biologically active. The wide range in therapeutic potential of benzoxazole derivatives is related to the favourable interactions of the benzoxazole moiety with different protein targets.Application In Synthesis of 2-(3-Bromophenyl)benzo[d]oxazole

Referemce:
Benzoxazole – Wikipedia,
Benzoxazole | C7H5NO – PubChem

Cyclopalladated ferrocenylimine catalyzed ortho-arylation of sp² C-H bond substrates containing the directing group was written by Li, Ya-Nan;Yang, Fan;Wu, Yang-Jie. And the article was included in Gaodeng Xuexiao Huaxue Xuebao in 2008.Quality Control of 2-(3-Bromophenyl)benzo[d]oxazole This article mentions the following:

A novel and efficient catalytic system for ortho-arylation of sp² C-H bond substrates containing the directing group using cyclopalladated ferrocenylimine as catalyst was developed. The arylation showed high regioselectivity and only occurred on the less sterically hindered ortho-C-H bond. The reaction could be compatible to diverse functional groups such as CH₃, CH₃O, and CH₃CO, as well as Br and Cl substituents, which would permit to be functionalized further to construct new compounds with more complicated structures. In the experiment, the researchers used many compounds, for example, 2-(3-Bromophenyl)benzo[d]oxazole (cas: 99586-31-9Quality Control of 2-(3-Bromophenyl)benzo[d]oxazole).

2-(3-Bromophenyl)benzo[d]oxazole (cas: 99586-31-9) belongs to benzoxazole derivatives. Benzoxazole nucleus is one of the most important heterocyclic compounds exhibiting remarkable pharmacological activities. A number of marketed drugs are available having benzoxazole as core active moiety like, nonsteroidal anti-inflammatory drug (NSAID)—flunoxaprofen, benoxaprofen, antibiotic—calcimycin.Quality Control of 2-(3-Bromophenyl)benzo[d]oxazole

Referemce:
Benzoxazole – Wikipedia,
Benzoxazole | C7H5NO – PubChem

Facile synthesis of 3-arylpyridine derivatives by palladacycle-catalyzed Stille cross-coupling reaction was written by Ma, Gaizhi;Leng, Yuting;Wu, Yusheng;Wu, Yangjie. And the article was included in Tetrahedron in 2013.Electric Literature of C13H8BrNO This article mentions the following:

The Stille cross-coupling reaction of a variety of aryl halides (X = Cl, Br, I) with 3- or 2-(trialkylstannyl)pyridines was catalyzed by cyclopalladated ferrocenylimine. This reaction allows formation of arylpyridine derivatives in moderate to excellent yields. Functional groups on the aryl halides, such as amino, hydroxyl, keto, and formyl, are tolerated and the reactions with arylbenzoxazole substrates also proceeded well. In the experiment, the researchers used many compounds, for example, 2-(3-Bromophenyl)benzo[d]oxazole (cas: 99586-31-9Electric Literature of C13H8BrNO).

2-(3-Bromophenyl)benzo[d]oxazole (cas: 99586-31-9) belongs to benzoxazole derivatives. Its aromaticity makes it relatively stable, although as a heterocycle, it has reactive sites which allow for functionalization. Benzoxazoles are prominent in medicinal chemistry due to their wide spectrum of pharmacological activities such as anti-inflammatory, antimycobacterial, antihistamine.Electric Literature of C13H8BrNO

Referemce:
Benzoxazole – Wikipedia,
Benzoxazole | C7H5NO – PubChem

N-Acylbenzotriazole as Efficient Ligand in Copper-Catalyzed O-Arylation Leading to Diverse Benzoxazoles was written by Singh, Anoop S.;Singh, Mala;Mishra, Nidhi;Mishra, Snigdha;Agrahari, Anand K.;Tiwari, Vinod K.. And the article was included in ChemistrySelect in 2017.Category: benzoxazole This article mentions the following:

An establishment of (1H-benzo[d][1,2,3]triazol-1-yl)(2-methoxyphenyl)methanone as ligand was attained in intramol. C-O cross-coupling of N-(2-halophenyl)aryl/alkylamide derivatives XC₆H₄NHC(O)R [R = (CH₂)₁₀CH₃, C₆H₅, 2-H₃CC₆H₄, etc.; X = 2-Cl, 2-Br, 2,6-Cl₂-4-Br] to form 2-aryl/alkyl benzoxazole derivatives I (Y = H, 4-Cl-6-Br) using CuI/K₂CO₃ as catalytic system. Salient advantages associated with this pathway include easily available starting materials, cheap catalyst, highly stable ligand, wide substrate scope, smooth reaction, easy work-up and high product yield. In the experiment, the researchers used many compounds, for example, 2-(3-Bromophenyl)benzo[d]oxazole (cas: 99586-31-9Category: benzoxazole).

2-(3-Bromophenyl)benzo[d]oxazole (cas: 99586-31-9) belongs to benzoxazole derivatives. Benzoxazoles belong to the group of well-known antifungal agents with antioxidant, antiallergic, antitumoral and antiparasitic activity. The wide range in therapeutic potential of benzoxazole derivatives is related to the favourable interactions of the benzoxazole moiety with different protein targets.Category: benzoxazole

Referemce:
Benzoxazole – Wikipedia,
Benzoxazole | C7H5NO – PubChem

Palladium catalyzed C_sp²-H activation for direct aryl hydroxylation: the unprecedented role of 1,4-dioxane as a source of hydroxyl radicals was written by Seth, Kapileswar;Nautiyal, Manesh;Purohit, Priyank;Parikh, Naisargee;Chakraborti, Asit K.. And the article was included in Chemical Communications (Cambridge, United Kingdom) in 2015.Name: 2-(3-Bromophenyl)benzo[d]oxazole This article mentions the following:

A novel strategy for direct aryl hydroxylation via Pd-catalyzed C_sp²-H activation through an unprecedented hydroxyl radical transfer from 1,4-dioxane, used as a solvent, is reported with bio relevant and sterically hindered heterocycles and various acyclic functionalities as versatile directing groups. In the experiment, the researchers used many compounds, for example, 2-(3-Bromophenyl)benzo[d]oxazole (cas: 99586-31-9Name: 2-(3-Bromophenyl)benzo[d]oxazole).

2-(3-Bromophenyl)benzo[d]oxazole (cas: 99586-31-9) belongs to benzoxazole derivatives. Its aromaticity makes it relatively stable, although as a heterocycle, it has reactive sites which allow for functionalization. The wide range in therapeutic potential of benzoxazole derivatives is related to the favourable interactions of the benzoxazole moiety with different protein targets.Name: 2-(3-Bromophenyl)benzo[d]oxazole

Referemce:
Benzoxazole – Wikipedia,
Benzoxazole | C7H5NO – PubChem

Lewis-Acid-Mediated Benzotriazole Ring Cleavage (BtRC) Strategy for the Synthesis of 2-Aryl Benzoxazoles from N-Acylbenzotriazoles was written by Singh, Anoop S.;Mishra, Nidhi;Kumar, Dhananjay;Tiwari, Vinod K.. And the article was included in ACS Omega in 2017.HPLC of Formula: 99586-31-9 This article mentions the following:

A Lewis-acid-mediated ring cleavage of acylbenzotriazoles (RCOBt) followed by cyclization to corresponding benzoxazoles was achieved in good to excellent yields. The reaction was found consistent with the milligram to gram scale. In the experiment, the researchers used many compounds, for example, 2-(3-Bromophenyl)benzo[d]oxazole (cas: 99586-31-9HPLC of Formula: 99586-31-9).

2-(3-Bromophenyl)benzo[d]oxazole (cas: 99586-31-9) belongs to benzoxazole derivatives. Benzoxazole nucleus is one of the most important heterocyclic compounds exhibiting remarkable pharmacological activities. Benzoxazoles are prominent in medicinal chemistry due to their wide spectrum of pharmacological activities such as antiparkinson, inhibition of hepatitis C virus, 5-HT3 antagonistic effect.HPLC of Formula: 99586-31-9

Referemce:
Benzoxazole – Wikipedia,
Benzoxazole | C7H5NO – PubChem

Platinum(II) complexes based on phenylbenzoazole-derived ligands for phosphorescent organic light-emitting diodes was written by Kang, Soo Kyung;Hwang, Namhee;Pak, Soyoung;Kim, Young Kwan;Yoon, Seung Soo. And the article was included in Journal of Nanoscience and Nanotechnology in 2020.Recommanded Product: 2-(3-Bromophenyl)benzo[d]oxazole This article mentions the following:

Phosphorescent Pt(II) complexes based on phenylbenzoazole ligands were synthesized and their photophys. properties were investigated for OLEDs. Multilayered OLEDs devices using these complexes as emitters showed the efficient emissions, which are very sensitive to the structural and photophys. properties of Pt(II) complexes. In particularly, a device C using Pt(II) complex 2 based on phenylbenzoazole ligand as the dopant exhibited efficient emission with a luminous efficiency, a power efficiency, an external quantum efficiency, and CIE coordinates of 8.03 cd/A, 2.79 Im/W, 4.84% at 20 mA/cm2, and (0.63, 0.35) at 10.0 V, resp. In the experiment, the researchers used many compounds, for example, 2-(3-Bromophenyl)benzo[d]oxazole (cas: 99586-31-9Recommanded Product: 2-(3-Bromophenyl)benzo[d]oxazole).

2-(3-Bromophenyl)benzo[d]oxazole (cas: 99586-31-9) belongs to benzoxazole derivatives. Benzoxazole nucleus is one of the most important heterocyclic compounds exhibiting remarkable pharmacological activities. Benzoxazoles are prominent in medicinal chemistry due to their wide spectrum of pharmacological activities such as antibacterial, antifungal, anticancer.Recommanded Product: 2-(3-Bromophenyl)benzo[d]oxazole

Referemce:
Benzoxazole – Wikipedia,
Benzoxazole | C7H5NO – PubChem

An efficient synthesis of 2-substituted benzoxazoles via RuCl₃.3H₂O catalyzed tandem reactions in ionic liquid was written by Fan, Xuesen;He, Yan;Wang, Yangyang;Zhang, Xinying;Wang, Jianji. And the article was included in Chinese Journal of Chemistry in 2011.Reference of 99586-31-9 This article mentions the following:

An efficient synthesis of 2-substituted benzoxazoles through RuCl₃.3H₂O-catalyzed, air-oxidized tandem reactions of 2-aminophenols and aldehydes in [bmim]BF₄ was developed. This synthetic strategy has such advantages as mild reaction conditions, cost-free oxidant, readily available starting materials, and recyclable catalyst and solvent. It was successfully used in the synthesis of new 5-(benzoxazol-2-yl)-2′-deoxyuridines. In the experiment, the researchers used many compounds, for example, 2-(3-Bromophenyl)benzo[d]oxazole (cas: 99586-31-9Reference of 99586-31-9).

2-(3-Bromophenyl)benzo[d]oxazole (cas: 99586-31-9) belongs to benzoxazole derivatives. Benzoxazole derivatives have different biological activities. Benzoxazoles are prominent in medicinal chemistry due to their wide spectrum of pharmacological activities such as antiparkinson, inhibition of hepatitis C virus, 5-HT3 antagonistic effect.Reference of 99586-31-9

Referemce:
Benzoxazole – Wikipedia,
Benzoxazole | C7H5NO – PubChem