Tag: M.W:100-200

In organic chemistry, atoms other than carbon and hydrogen are generally referred to as heteroatoms. The most common heteroatoms are nitrogen, oxygen and sulfur. Now I present to you an article called Pyrolysis of carbohydrates. Analysis of industrial caramel vapors, published in 1989-08-31, which mentions a compound: 3194-15-8, mainly applied to carbohydrate caramelization gas composition; glucose pyrolysis gas composition; sucrose pyrolysis gas composition, Safety of 1-(Furan-2-yl)propan-1-one.

Twenty nine compounds were identified by gas chromatog./mass spectrometry in the gaseous products from pyrolysis of glucose and sucrose under conditions of caramel manufacture The main product was 5-hydroxymethylfurfural (70-90%, depending on pyrolysis conditions). The compound was formed more easily from sucrose than from glucose, and its yield increased with increasing pyrolysis temperature Aliphatic and keto acids, heterocyclic compounds with furan or pyran ring, aromatic compounds, and bisfuran compounds were formed in minor amounts

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Reference:
Benzoxazole – Wikipedia,
Benzoxazole | C7H5NO – PubChem

COA of Formula: C8H8N2S. The protonation of heteroatoms in aromatic heterocycles can be divided into two categories: lone pairs of electrons are in the aromatic ring conjugated system; and lone pairs of electrons do not participate. Compound: 2-Mercapto-5-methylbenzimidazole, is researched, Molecular C8H8N2S, CAS is 27231-36-3, about New accelerator-cum-antioxidants for chloroprene rubber. Author is Khanra, Tapan Kumar; Maiti, Sukumar; Adhikari, Basudam.

2-Mercaptoimidazole (MI), N-methyl-2-mercaptoimidazole (MMI), 2-mercaptobenzimidazole (MBI), 5-methyl-2-mercaptobenzimidazole (MMBI) and 5-nitro-2-mercaptobenzimidazole (NMBI) have been tried as the crosslinking agent for chloroprene rubber (Neoprene W). Apart from the curing ability, these imidazole derivatives have also shown antioxidant properties. 1-(N-oxydiethylene thiocarbamyl)-2-(N-oxydiethylene thio)benzimidazole (MBSPT), a novel dual function accelerator-cum-antioxidant for diene rubbers, has also been used in Neoprene W. The cure characteristics, phys. properties of the vulcanizates and their aging behavior of stocks containing these imidazole derivatives, ethylene thiourea (Na-22) and MBSPT have been compared. Some of the compounds viz. MBSPT, MBI and MI may be prescribed as secondary accelerator-cum-antioxidants with some primary accelerator for filled neoprene rubber.

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Reference:
Benzoxazole – Wikipedia,
Benzoxazole | C7H5NO – PubChem

Name: 2-Mercapto-5-methylbenzimidazole. Aromatic compounds can be divided into two categories: single heterocycles and fused heterocycles. Compound: 2-Mercapto-5-methylbenzimidazole, is researched, Molecular C8H8N2S, CAS is 27231-36-3, about Strong intra- and intermolecular aurophilic interactions in a new series of brilliantly luminescent dinuclear cationic and neutral Au(I) benzimidazolethiolate complexes. Author is Schneider, Jacob; Lee, Young-A.; Perez, Javier; Brennessel, William W.; Flaschenriem, Christine; Eisenberg, Richard.

The structural and photophys. properties of a new series of cationic and neutral Au(I) dinuclear compounds bridged by bis(diphenylphosphino)methane (dppm) and 5-X-substituted benzimidazolethiolate (X-BIT) ligands, where X = H (a), Me (b), OMe (c), and Cl (d), have been studied. Monocationic complexes [Au2(μ-X-BIT)(μ-dppm)](CF3CO2) (1) were prepared by the reaction of [Au2(μ-dppm)](CF3CO2)2 with 1 equiv of X-BIT in excellent yields. The cations 1a-1d possess similar mol. structures, each with a linear coordination geometry around the Au(I) nuclei, as well as relatively short intramol. Au(I)···Au(I) separations ranging between 2.88907(6) Å for 1d and 2.90607(16) Å for 1a indicative of strong aurophilic interactions. The cations are violet luminescent in CH2Cl2 solution with a λemmax of ca. 365 nm, assigned as ligand-based or metal-centered (MC) transitions. Three of the cationic complexes, 1a, 1b and 1d, exhibit unusual luminescence tribochromism in the solid-state, in which the photoemission is shifted significantly to higher energy upon gentle grinding of microcrystalline samples with ΔE = 1130 cm-1 for 1a, 670 cm-1 (1b), and 870 cm-1 (1d). The neutral dinuclear complexes [Au2(μ-X-BIT)(μ-dppm)] (2a-2d) were formed in good yields by the treatment of a CH2Cl2 solution of cationic compounds 1a-1d with NEt3. Complexes 2a-2d aggregate to form dimers having substantial intra- and intermol. aurophilic interactions with unsupported Au(I)···Au(I) intermol. distances in the range of 2.8793(4)-2.9822(8) Å, compared with intramol. bridge-supported separations of 2.8597(3)-2.9162(3) Å. Complexes 2a-2d exhibit brilliant luminescence in the solid-state and in DMSO solution with red-shifted λemmax energies in the range of 485-545 nm that are dependent on X-BIT and assigned as ligand-to-metal-metal charge transfer (LMCT) states based in part on the extended Au···Au interactions.

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Reference:
Benzoxazole – Wikipedia,
Benzoxazole | C7H5NO – PubChem

The three-dimensional configuration of the ester heterocycle is basically the same as that of the carbocycle. Compound: 1-(Furan-2-yl)propan-1-one(SMILESS: O=C(C1=CC=CO1)CC,cas:3194-15-8) is researched.Reference of (R)-Piperidin-3-ol hydrochloride. The article 《Hydrothermal formation of hydroxylated benzenes from furan derivatives》 in relation to this compound, is published in Journal of Analytical and Applied Pyrolysis. Let’s take a look at the latest research on this compound (cas:3194-15-8).

Several furan derivatives were subjected to hydrothermolysis at 340° and 27.5 MPa for 1-33 min in a flow system to study their conversion to hydroxylated benzenes. Hydrothermolysis of 0.05M aqueous 5-methyl-2-furaldehyde, 2-acetylfuran and 2-propionylfuran gave 1,4-benzenediol, 1,2-benzenediol and 3-methyl-1,2-benzenediol, resp., with selectivities ranging from 10-65%. Hydrothermolysis of 0.01M aqueous 2-acetyl-5-(hydroxymethyl)furan and 5-(1-hydroxyethyl)-2-furaldehyde did not produce the expected benzenetriols; instead, 2-methyl-1,4-benzenediol could be identified as a product. Hydrothermolysis of 2-vinylfuran did not produce any phenol, an indication that the formation of benzene rings from furans is not accomplished by electrocyclic ring closure. 2,6-Dimethyl-γ-pyrone, a compound that is known to produce 5-methyl-1,3-benzenediol via an aldol condensation under alk. conditions, also gave this product under hydrothermal conditions. A reaction pathway for the hydrothermal formation of hydroxylated benzenes from furan derivatives is presented which is based on C ring formation via an intramol. aldol condensation.

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Reference:
Benzoxazole – Wikipedia,
Benzoxazole | C7H5NO – PubChem

COA of Formula: C9H9NO. The mechanism of aromatic electrophilic substitution of aromatic heterocycles is consistent with that of benzene. Compound: 2-Ethylbenzo[d]oxazole, is researched, Molecular C9H9NO, CAS is 6797-13-3, about Reaction of benzoxa(thia)zoles with allenylmagnesium bromide. Synthesis of propargylbenzothiazolines and dipropargylalkyl-o-aminophenols. Author is Babudri, F.; Florio, S..

Benzoxazoles I (R = H, alkyl, CH2Ph; X = O) and benzothiazole I (R = H; X = S) react with H2C:C:CHMgBr (II) (prepared from propargyl bromide) to give 2-HOC6H4NHC(CH2CCH)2R and disulfide III resp. The reaction of I (R = alkyl, CH2Ph; X = S) with II gives the propargylbenzothiazolines IV and I (R = OMe; X = S) produces I (R = CH:C:CH2; X = S).

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Reference:
Benzoxazole – Wikipedia,
Benzoxazole | C7H5NO – PubChem

Application of 6797-13-3. Aromatic heterocyclic compounds can also be classified according to the number of heteroatoms contained in the heterocycle: single heteroatom, two heteroatoms, three heteroatoms and four heteroatoms. Compound: 2-Ethylbenzo[d]oxazole, is researched, Molecular C9H9NO, CAS is 6797-13-3, about Tungstate sulfuric acid as an efficient catalyst for the synthesis of benzoxazoles and benzothiazoles under solvent-free conditions. Author is Farahi, Mahnaz; Karami, Bahador; Azari, Masume.

Tungstate sulfuric acid (TSA) was found to be an efficient and reusable catalyst for the synthesis of benzoxazole and benzothiazole derivatives via reactions of ortho esters with o-aminophenols or o-aminothiophenols in high yields.

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Reference:
Benzoxazole – Wikipedia,
Benzoxazole | C7H5NO – PubChem

The preparation of ester heterocycles mostly uses heteroatoms as nucleophilic sites, which are achieved by intramolecular substitution or addition reactions. Compound: 2-Mercapto-5-methylbenzimidazole( cas:27231-36-3 ) is researched.Synthetic Route of C8H8N2S.Sorba, Giovanni; Garrone, Adele; Serafino, Anna; Gasco, Alberto; Orsetti, Marco published the article 《Potential histamine H2-receptor antagonists: ranitidine analogs containing 2-amino-5(6)-substituted benzimidazole moieties. (1)》 about this compound( cas:27231-36-3 ) in European Journal of Medicinal Chemistry. Keywords: ranitidine analog preparation antihistaminic; aminobenzimidazole preparation antihistaminic; structure antihistaminic activity aminobenzimidazole. Let’s learn more about this compound (cas:27231-36-3).

A series of ranitidine analogs (I: R = H, Me, OMe, Cl, CONH2, CN, and NO2) were synthesized and tested for its in vitro H2-antagonism by using the histamine induced guinea pig atria chronotropic response. These substances generally display good H2-antagonist activity. Some considerations of the structure relationships are also discussed, in particular the physicochem. properties of the benzimidazole moiety.

There is still a lot of research devoted to this compound(SMILES：SC1=NC2=CC(C)=CC=C2N1)Synthetic Route of C8H8N2S, and with the development of science, more effects of this compound(27231-36-3) can be discovered.

Reference:
Benzoxazole – Wikipedia,
Benzoxazole | C7H5NO – PubChem

Hirano, Masaya; Fukumoto, Yoshiya; Matsubara, Nao; Chatani, Naoto published the article 《A cationic iridium-catalyzed C(sp3)-H silylation of 2-Alkyl-1,3-azoles at the α-position in the 2-alkyl group leading to 2-(1-Silylalkyl)-1,3-azoles》. Keywords: cationic iridium catalyzed regioselective silylation alkylazole alpha position alkyl; silylalkylazole preparation.They researched the compound: 2-Ethylbenzo[d]oxazole( cas:6797-13-3 ).Product Details of 6797-13-3. Aromatic heterocyclic compounds can be divided into two categories: single heterocyclic and fused heterocyclic. In addition, there is a lot of other information about this compound (cas:6797-13-3) here.

The regioselective silylation of the α-C(sp3)-H bond in the 2-alkyl group in 2-alkyl-1,3-azole derivatives with hydrosilanes, catalyzed by the combination of (POCOPtBu)IrHCl and NaBArF4, leading to the production of 2-(1-silylalkyl)-1,3-azoles is described. The presence of 3,5-dimethylpyridine is required for the reaction to proceed. Although the reaction takes place both in the presence and absence of a hydrogen acceptor, the addition of an acceptor gave better results, in terms of the efficiency of the reaction.

From this literature《A cationic iridium-catalyzed C(sp3)-H silylation of 2-Alkyl-1,3-azoles at the α-position in the 2-alkyl group leading to 2-(1-Silylalkyl)-1,3-azoles》,we know some information about this compound(6797-13-3)Product Details of 6797-13-3, but this is not all information, there are many literatures related to this compound(6797-13-3).

Reference:
Benzoxazole – Wikipedia,
Benzoxazole | C7H5NO – PubChem

The chemical properties of alicyclic heterocycles are similar to those of the corresponding chain compounds. Compound: 2-Mercapto-5-methylbenzimidazole, is researched, Molecular C8H8N2S, CAS is 27231-36-3, about In vitro cytotoxicity of the thyrotoxic and hepatotoxic rubber antioxidant 2-mercaptobenzimidazole and its 4- or 5-methyl derivatives in rabbit corneal cells, the main research direction is cytotoxicity hepatotoxicity thyrotoxicity mercaptobenzimidazole.Name: 2-Mercapto-5-methylbenzimidazole.

2-Mercaptobenzimidazole (MBI) and its Me derivatives 4-methyl-MBI (4-MeMBI), 5-methyl-MBI (5-MeMBI), and 4(or 5)-methyl-MBI (4(5)-MeMBI) are widely applied industrial agents with substantial thyrotoxicity and hepatotoxicity detected in rats in vivo. Here, we examined the in vitro cytotoxicity of MBI and its derivates in cultured SIRC rabbit corneal cells. SIRC cells were cultured in the presence of the test chems. for 72 h, and cell viability was determined by estimating the number of cells using a crystal violet staining assay. The median lethal concentration (LC50) was calculated for each of the chems. The Me derivatives showed higher cytotoxicity than MBI, which is in contrast to previous in vivo findings demonstrating higher thyrotoxicity and hepatotoxicity of MBI compared to its derivates. According to the LC50 values, the ranking of the tested agents in terms of cytotoxicity was 5-MeMBI (761.5μM) ≥ 4-MeMBI (796.3μM) ≥ 4(5)-MeMBI (822.9μM) > MBI (1002.9μM). The present results suggest that the lower thyrotoxicity and hepatotoxicity of Me derivatives of MBI is related to their faster detoxification in vivo, because SIRC cells are considered to have lower drug-metabolizing activity than hepatic cells.

From this literature《In vitro cytotoxicity of the thyrotoxic and hepatotoxic rubber antioxidant 2-mercaptobenzimidazole and its 4- or 5-methyl derivatives in rabbit corneal cells》,we know some information about this compound(27231-36-3)Name: 2-Mercapto-5-methylbenzimidazole, but this is not all information, there are many literatures related to this compound(27231-36-3).

Reference:
Benzoxazole – Wikipedia,
Benzoxazole | C7H5NO – PubChem

Recommanded Product: 3194-15-8. The mechanism of aromatic electrophilic substitution of aromatic heterocycles is consistent with that of benzene. Compound: 1-(Furan-2-yl)propan-1-one, is researched, Molecular C7H8O2, CAS is 3194-15-8, about Halogen effects in the reactions of benzylmagnesium halides with furfural and alkyl 2-furyl ketones. Author is Sjoholm, Rainer.

The reactions of PhCH2MgX (X = Cl, Br, I) with furans I (R = H, Me, Et, CHMe2, CMe3) gave 1,2- and 1,4-addition products. The halogen atom of the reagent had a marked effect on the product distribution when R was H, Me, or Et: the heavier the halogen atom, the more 1,2-addition products were formed at the expense of 1,4-addition products.

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Reference:
Benzoxazole – Wikipedia,
Benzoxazole | C7H5NO – PubChem