Tag: M.W=150-200

Liu, Min; Zeng, Meng-Tian; Xu, Wan; Wu, Li; Dong, Zhi-Bing published the artcile< Selective synthesis of 2-aminobenzoxazoles and 2-mercaptobenzoxazoles by using o-aminophenols as starting material>, Name: 5-Fluorobenzo[d]oxazole-2-thiol, the main research area is aminobenzoxazole mercaptobenzoxazole preparation aminophenol dithiocarbamate TMTD.

2-Aminobenzoxazoles and 2-mercaptobenzoxazoles were selectively synthesized by treating o-aminophenols with dithiocarbamates and tetramethylthiuram disulfide (TMTD), resp. With the promotion of NaH/CuI, the reaction of o-aminophenols with dithiocarbamates gave 2-aminobenzoxazoles with good yield (70-92%) in one pot manner, and 2-mercaptobenzoxazoles were synthesized (yield: 55-80%) in the presence of K2CO3 by treating o-aminophenols with tetramethylthiuram disulfide (TMTD). The feature of this method includes good to excellent yield, easy performance and broad substrate scope, which makes the protocol practical and attractive in the preparation of some potential pharmaceutically active compounds

Tetrahedron Letterspublished new progress about Amino phenols Role: RCT (Reactant), RACT (Reactant or Reagent). 13451-78-0 belongs to class benzoxazole, and the molecular formula is C7H4FNOS, Name: 5-Fluorobenzo[d]oxazole-2-thiol.

Referemce:
Benzoxazole – Wikipedia,
Benzoxazole | C7H5NO – PubChem

Varun, Begur Vasanthkumar; Gadde, Karthik; Prabhu, Kandikere Ramaiah published the artcile< Sulfenylation of β-Diketones Using C-H Functionalization Strategy>, Recommanded Product: 5-Fluorobenzo[d]oxazole-2-thiol, the main research area is bezoxazolethione diketone sulfenylation cross dehydrogenative coupling; bezoxazolyl sulfenylated diketone preparation.

Sulfenylation of β-diketones is challenging as β-diketones undergo deacylation after sulfenylation in the reaction medium. The sulfenylation of β-diketones without deacylation under metal-free conditions at ambient temperature via a cross dehydrogenative coupling (CDC) strategy is reported. The resultant products can be further manipulated to form α,α-disubstituted β-diketones and pyrazoles.

Organic Letterspublished new progress about Diketones, 1,3-diketones Role: RCT (Reactant), SPN (Synthetic Preparation), RACT (Reactant or Reagent), PREP (Preparation). 13451-78-0 belongs to class benzoxazole, and the molecular formula is C7H4FNOS, Recommanded Product: 5-Fluorobenzo[d]oxazole-2-thiol.

Referemce:
Benzoxazole – Wikipedia,
Benzoxazole | C7H5NO – PubChem

Yang, Hongpeng; Chen, Lei; Zhang, Shouguo; Wang, Gang; Chen, Tingting; Xu, Jing; Peng, Tao; Wang, Lin; Hu, Liming published the artcile< Synthesis and Application of a Thiol Photolabile Protecting Group>, Quality Control of 13451-78-0, the main research area is nitrophenylbutanyl hydroxymethyl carbamate preparation photolabile protecting group.

A photolabile protecting group (PLPG) for thiol that can be rapidly photolyzed by irradiation at 365 nm to release thiol groups within 100 s. was successfully designed and synthesized. The photolytic reaction has mild conditions and avoids acid cleavage, leading to good yields with no side reactions as validated by HPLC. The PLPG has good acid/alkali tolerance.

ChemistrySelectpublished new progress about Aromatic thiols Role: RCT (Reactant), SPN (Synthetic Preparation), RACT (Reactant or Reagent), PREP (Preparation). 13451-78-0 belongs to class benzoxazole, and the molecular formula is C7H4FNOS, Quality Control of 13451-78-0.

Referemce:
Benzoxazole – Wikipedia,
Benzoxazole | C7H5NO – PubChem