Synthesis of N-octadecylsquarylium dye was written by Tanaka, Motoo;Sekiguchi, Tatsuo;Kawabata, Yasujiro;Nakamura, Takayoshi;Manda, Eiichiro. And the article was included in Nippon Kagaku Kaishi in 1987.Recommanded Product: 5676-58-4 This article mentions the following:
The synthesis of N-octadecylsquarylium dyes I (R = H, Me, OMe, Cl; X = CMe2, S, Se) and II (R1 = Me, Et; R2 = H, Me, OH) was studied. A mixture of 2 mol N-octadecylated intermediate and 1 mol squaric acid was refluxed 24 h in 2:3 (volume) PhCl-1-pentanol (Method A), or heated 5 h at 160° in the presence of Nafion H resin (Method B). Method B gave better yields than method A. The yields of I were affected by the electronegativity of X and were in the order CMe2 > Se > S > O. In the case of II good yields were attained for R2 which was an electron-releasing substituent such as OH or Me. IR and NMR measurements revealed that I and II had sym. 1,3-bonded squarylium rings, consistent with the results of N-Me squarylium dyes reported by A. Treibs and K. Jacob (1966,1698). In the experiment, the researchers used many compounds, for example, 2,5-Dimethylbenzoxazole (cas: 5676-58-4Recommanded Product: 5676-58-4).
2,5-Dimethylbenzoxazole (cas: 5676-58-4) belongs to benzoxazole derivatives. The benzoxazole moiety is widely found in various natural compounds, which are often found to be biologically active. It is found within the chemical structures of pharmaceutical drugs such as flunoxaprofen and tafamidis.Recommanded Product: 5676-58-4
Referemce:
Benzoxazole – Wikipedia,
Benzoxazole | C7H5NO – PubChem