Synthesis through microwave irradiation, characterization and evaluation of antimicrobial activity of 2-phenyl-1,3-benzoxazole derivatives was written by Tariq, Sana;Wakode, Sharad. And the article was included in International Research Journal of Pharmacy in 2012.HPLC of Formula: 99586-31-9 This article mentions the following:
2-Phenyl-1,3-benzoxazoles were synthesized by the reaction of 2-aminophenol and acyl chlorides using microwave irradiation The compounds were evaluated for in-vitro antimicrobial activity against Bacillus pumilus, Bacillus subtilis (Gram pos.); Escherichia coli, Pseudomonas aeruginosa (Gram neg.); and Candida albicans and Aspergillus niger by agar-well diffusion at 2.5, 5, and 10 mg/mL. 2-(2-Methoxyphenyl)-, 2-(4-bromophenyl)-, 2-(3-chlorophenyl)-, and 2-(2-nitrophenyl)-1,3-benzoxazole exhibited good antibacterial activity. 2-Phenyl- and 2-(4-bromophenyl)-1,3-benzoxazole were potent antifungal compounds amongst the series. In the experiment, the researchers used many compounds, for example, 2-(3-Bromophenyl)benzo[d]oxazole (cas: 99586-31-9HPLC of Formula: 99586-31-9).
2-(3-Bromophenyl)benzo[d]oxazole (cas: 99586-31-9) belongs to benzoxazole derivatives. Benzoxazole nucleus is one of the most important heterocyclic compounds exhibiting remarkable pharmacological activities. Benzoxazoles are prominent in medicinal chemistry due to their wide spectrum of pharmacological activities such as anti-inflammatory, antimycobacterial, antihistamine.HPLC of Formula: 99586-31-9
Referemce:
Benzoxazole – Wikipedia,
Benzoxazole | C7H5NO – PubChem