In an article, author is Tasci, Meryem, once mentioned the application of 2343-89-7, SDS of cas: 2343-89-7, Name is Methyl 2-fluoroacrylate, molecular formula is C4H5FO2, molecular weight is 104.0797, MDL number is MFCD04039286, category is benzoxazole. Now introduce a scientific discovery about this category.
Synthesis and antimicrobial evaluation of novel 5-substituted-2-(p-tert-butylphenyl)benzoxazoles
In the present study, a series of nine novel 5-substituted-2-(p-tert-butylphenyl)benzoxazole derivatives have been synthesized and their structures confirmed by spectral techniques and also tested for their antimicrobial activities. The minimum inhibitory concentrations (MIC) of the new benzoxazoles have been determined against standard bacterial and fungal strains and drug-resistant isolates and compared to those of several reference drugs. The new benzoxazole derivatives are found to possess a broad spectrum of antibacterial activity with MIC values of 8-256 mu g/mL. Especially, compound 9 is more active than standard drugs ciprofloxacin and cefotaxime against E. coli isolate with a MIC value of 8 mu g/mL. Also new compounds are less active than fluconazole with a MIC value of 256 mu g/mL against C. albicans and its isolate except for compound 9 that shows better activity other compounds with a MIC value of >4 mu g/mL for their antifungal activity.
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Reference:
Benzoxazole – Wikipedia,
,Benzoxazole | C7H5NO – PubChem