The effect of the change of synthetic route on the product 3194-15-8

After consulting a lot of data, we found that this compound(3194-15-8)Electric Literature of C7H8O2 can be used in many types of reactions. And in most cases, this compound has more advantages.

Janda, Miroslav; Kurc, Jozef published an article about the compound: 1-(Furan-2-yl)propan-1-one( cas:3194-15-8,SMILESS:O=C(C1=CC=CO1)CC ).Electric Literature of C7H8O2. Aromatic heterocyclic compounds can be classified according to the number of heteroatoms or the size of the ring. The authors also want to convey more information about this compound (cas:3194-15-8) through the article.

So-called junipal (5-(1-propynyl)-2-thiophenecarboxaldehyde) was compared with 5-propionyl-2-thiophenecarboxaldehyde and similar compounds of the furan and thiophene series in inhibiting the growth of E. coli B. The biol. activity of junipal seemed to be very sensitive to structural changes. The tested compounds were 2-(R1-substituted)-5-(R2-substituted)thiophenes (I) and 2-(R1-substituted)-5-(R2-substituted)furans (II), with R1 and R2 in I being, resp., HCO, MeCC; HCO, EtCO; H, MeCC; H, EtCO; H, MeCH:CH; H, EtCH(OH); H, MeCO; H, CHO; CO2H, Et; and in II, H, EtCO; H, EtCH(OH); CO2H, CH2CO2H; CO2H, CH:CHCO2H. A new method was used for preparation of II (H, EtCO): reaction of EtMgBr with the Na salt of 2-furoic acid. The toxicity of junipal against E. coli was relatively high. Each structural change of junipal was accompanied by diminution of the inhibition.

After consulting a lot of data, we found that this compound(3194-15-8)Electric Literature of C7H8O2 can be used in many types of reactions. And in most cases, this compound has more advantages.

Reference:
Benzoxazole – Wikipedia,
Benzoxazole | C7H5NO – PubChem