Name is 5-Bromobenzo[d]oxazole, as a common heterocyclic compound, it belongs to benzoxazole compound, and cas is 132244-31-6, its synthesis route is as follows.,132244-31-6
198 mg (ie 1 mmol) of 5-bromobenzoxazole, 203 mg (ie 1.5 mmol) of 2-methyl-3-bromopropene, 240 mg (ie 3 mmol) of lithium tert-butoxide and 10 mg 0.1mmol) cuprous chloride, then add 2mL toluene, stirred at 110oC for 2 hours, after the reaction was concentrated to a petroleum ether: ethyl acetate volume ratio of 250: 1 as eluant by silica gel column chromatography to obtain5-bromo-2- (2-methyl-1-propenyl) benzoxazole, which structural formula is as follows:The compound was a light yellow solid in 80% yield with NMR data as follows:
With the complex challenges of chemical substances, we look forward to future research findings about 5-Bromobenzo[d]oxazole
Reference£º
Patent; Inner Mongolia University; Chen Shufeng; Li Die; (6 pag.)CN107266386; (2017); A;,
Benzoxazole – Wikipedia
Benzoxazole | C7H5NO – PubChem