It is a common heterocyclic compound, the benzoxazole compound, 6-Bromobenzo[d]oxazol-2(3H)-one, cas is 19932-85-5 its synthesis route is as follows.
To a deoxygenated mixture of tert-butyl ( (5- (4, 4, 5, 5-tetramethyl-1, 3, 2-dioxaborolan-2- yl) pyridin-2-yl) methyl) carbamate (62.5 mg, 0.187 mmol) , 6-bromobenzo oxazol-2 (3H) -one (40.0 mg, 0.187 mmol) , cesium carbonate (183 mg, 0.561 mmol) in DMF (0.93 mL) was added PdCl2(dppf) (21 mg, 0.028 mmol) and water (0.033 mL, 1.9 mmol) and the resulting mixture was heated at 140 for 30 min under microwave irradiation. The mixture was cooled and partitioned between EtOAc and water. The organic layer was washed with brine, dried over magnesium sulfate, and concentrated. The residue was purified by column chromatography on silica gel (0-5 MeOH in EtOAc) to afford the Boc protected intermediate. To a solution of this intermediate (18 mg, 0.053 mmol) in DCM (0.18 mL) was bubbled gaseous HCl for 1 min. The mixture was stirred for 1 h and then concentrated to afford the title compound. MS: m/z 242.24 (M + 1)
19932-85-5, In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles.,19932-85-5 ,6-Bromobenzo[d]oxazol-2(3H)-one, other downstream synthetic routes, hurry up and to see
Reference：
Patent; MERCK SHARP & DOHME CORP.; COOKE, Andrew J.; PITTS, Daniel; JOHNSON, Adam; BESHORE, Douglas C.; HURZY, Danielle; MITCHELL, Helen; FRALEY, Mark; MCCOMAS, Casey; SCHIRRIPA, Kathy; MERCER, Swati P.; NANDA, Kausik; MENG, Dongfang; WU, Jane; BABAOGLU, Kerim; LI, Chun Sing; MAO, Qinghua; QI, Zhiqi; (156 pag.)WO2016/54807; (2016); A1;,
Benzoxazole – Wikipedia
Benzoxazole | C7H5NO – PubChem