Chemistry is the experimental science by definition. We want to make observations to prove hypothesis. For this purpose, we perform experiments in the lab. , Formula: C6HF5, 363-72-4, Name is Pentafluorobenzene, molecular formula is C6HF5, belongs to benzoxazole compound. In a document, author is Kumar, Jogendra, introduce the new discover.
Pd-II-Catalyzed methoxylation of C(sp(3))-H bonds adjacent to benzoxazoles and benzothiazoles
The Pd(OAc)(2)/PhI(OAc)(2) catalyst system promotes the highly regioselective dehydrogenative methoxylation of a C(sp(3))-H bond adjacent to benzoxazole and benzothiazole rings. The title transformation constitutes the first example of a Pd-catalyzed C(sp(3))-H activating methoxylation at the proximal-selective a-position with regard to a directing auxiliary and provides expedient access to an important class of azole-decorated methyl ethers (up to 90% isolated yield). The synthetic practicality of the methodology was demonstrated by achieving a-methoxyacetic acids via the elimination of the benzoxazole auxiliaries and by obtaining the precursor of an O-methylated Breslow intermediate.
A reaction mechanism is the microscopic path by which reactants are transformed into products. Each step is an elementary reaction. In my other articles, you can also check out more blogs about 363-72-4. Formula: C6HF5.
Reference:
Benzoxazole – Wikipedia,
,Benzoxazole | C7H5NO – PubChem