Wang, Guang-cheng; Wang, Jing; Li, Lu-yao; Chen, Shan; Peng, Ya-ping; Xie, Zhen-zhen; Chen, Ming; Deng, Bin; Li, Wen-biao published the artcile< Synthesis of N-aryl-2-aminobenzoxazoles from substituted benzoxazole-2-thiol and 2-chloro-N-arylacetamides in KOH-DMF system>, HPLC of Formula: 13451-78-0, the main research area is aminobenzoxazole aryl preparation; benzoxazole thiol arylacetamide chloro condensation.
A simple and novel method for the synthesis of N-aryl-2-aminobenzoxazoles I [R1 = H, 5-F, 6-Me, etc. ; R2 = 4-Cl, 2,4-di-Me, 4-OPh, etc.] from substituted benzoxazole-2-thiols II and 2-chloro-N-arylacetamides R2C6H4NHC(O)CH2Cl in KOH-DMF system has been developed. The present protocol provides an attractive approach to access various N-aryl-2-aminobenzoxazoles I in moderate to good yields without using transition metal catalyst under very mild reaction condition.
Heterocycles published new progress about Acetamides Role: RCT (Reactant), RACT (Reactant or Reagent). 13451-78-0 belongs to class benzoxazole, and the molecular formula is C7H4FNOS, HPLC of Formula: 13451-78-0.
Referemce:
Benzoxazole – Wikipedia,
Benzoxazole | C7H5NO – PubChem