TEMPO-Mediated C-H Amination of Benzoxazoles with N-Heterocycles was written by Wang, Jian;Li, Jiang-Hua;Guo, Yidong;Dong, Hongbo;Liu, Qiang;Yu, Xiao-Qi. And the article was included in Journal of Organic Chemistry in 2020.Related Products of 132227-03-3 This article mentions the following:
The direct amination of benzoxazoles at C2 using N-heterocycles as nitrogen sources has been developed for the first time. Several kinds of inexpensive oxidants and also electricity were effective for this transformation in the presence of 2,2,6,6-tetramethylpiperidine-N-oxyl. This metal-free and operationally simple reaction can afford a variety of important C,N’-linked bis-heterocycles in moderate to good yields under very mild reaction conditions. The in situ generated oxoammonium salt was proved to be important for this transformation. In the experiment, the researchers used many compounds, for example, 5-Methoxybenzo[d]oxazole (cas: 132227-03-3Related Products of 132227-03-3).
5-Methoxybenzo[d]oxazole (cas: 132227-03-3) belongs to benzoxazole derivatives. Its aromaticity makes it relatively stable, although as a heterocycle, it has reactive sites which allow for functionalization. Due to its versatile biological properties, benzoxazole has been incorporated as an essential pharmacophore and substructure in many medicinal compounds.Related Products of 132227-03-3
Referemce:
Benzoxazole – Wikipedia,
Benzoxazole | C7H5NO – PubChem