Chemistry is the science of change. But why do chemical reactions take place? Why do chemicals react with each other? The answer is in thermodynamics and kinetics, Quality Control of 1,3-Diphenylisobenzofuran, 5471-63-6, Name is 1,3-Diphenylisobenzofuran, SMILES is C1(C2=CC=CC=C2)=C3C=CC=CC3=C(C4=CC=CC=C4)O1, belongs to benzoxazole compound. In a document, author is Gergely, Mate, introduce the new discover.
2-Aminobenzimidazole and -benzoxazole as N-nucleophile in palladium-catalysed aminocarbonylation
Palladium-catalysed aminocarbonylation of aryl iodides in the presence of 2-aminobenzimidazole and 2-aminobenzoxazole as N-nucleophile was carried out. Single CO insertion took place, however, instead of the expected carboxamides (C(O)NH) the corresponding N-acyl-imine (C(O)N=C) derivatives were obtained. The structure of the latter compounds can be explained by tautomerization involving the heterocyclic ring. The above structures without amide-NH moieties were proved by methylation at the NH groups of the heterocycle. The resulted mono- and dimethylated benzimidazole derivatives, as well as monomethylated benzoxazole derivatives, like the parent N-acylated compounds, were fully characterised including single crystal X-ray crystallography. (C) 2020 Published by Elsevier Ltd.
A reaction mechanism is the microscopic path by which reactants are transformed into products. Each step is an elementary reaction. In my other articles, you can also check out more blogs about 5471-63-6. Quality Control of 1,3-Diphenylisobenzofuran.
Reference:
Benzoxazole – Wikipedia,
,Benzoxazole | C7H5NO – PubChem