Wright, Adam J. published the artcilePlanar Chiral Pseudo-Isocoumarins by Copper Catalysed Desymmetrisation, Formula: C33H29N3O3, the publication is European Journal of Inorganic Chemistry (2022), 2022(12), e202100841, database is CAplus.
A new Cu catalyzed desymmetrization reaction of bisalkynyl ferrocenecarboxylic acids using (R,R)-Ph-Pybox results in the 1st asym. synthesis of planar chiral pseudo-isocoumarins in up to 64% enantiomeric excess and up to 99% yield with complete regioselectivity. Tri-functionalized planar chiral ferrocenes were synthesized in five steps from com. available materials, without the need for traditional directing group chem. via an easily diversified route exploiting the double Sonogashira coupling reaction. The absolute configuration of the chiral heterocycles is proven by chem. correlation and CD spectroscopy giving the asym. reaction synthetic utility and opening the way for the rational extension of this method to produce bioactive isocoumarin-fused ferrocene derivatives
European Journal of Inorganic Chemistry published new progress about 1239015-11-2. 1239015-11-2 belongs to benzoxazole, auxiliary class TOX Ligands, name is (3aS,3a’S,3a”S,8aR,8a’R,8a”R)-2,2′,2″-(Propane-1,2,2-triyl)tris(8,8a-dihydro-3aH-indeno[1,2-d]oxazole), and the molecular formula is C6H10O7, Formula: C33H29N3O3.
Referemce:
https://en.wikipedia.org/wiki/Benzoxazole,
Benzoxazole | C7H5NO – PubChem