One-pot copper-catalyzed aerobic decarboxylative coupling of phenylacetic acids with o-aminobenzenes and dioxygen as the oxidant leading to benzoxazoles and benzothiazoles was written by Yang, Daoshan;Yan, Kelu;Wei, Wei;Tian, Laijin;Shuai, Yuanyuan;Li, Ruixia;You, Jinmao;Wang, Hua. And the article was included in Asian Journal of Organic Chemistry in 2014.Electric Literature of C13H8BrNO This article mentions the following:
A simple and practical copper-catalyzed one-pot method for the synthesis of benzoxazole and benzothiazole derivatives I (X = O, S; R1 = H, 5-CH3, 6-Cl, 6-Br; R2 = H, 4-CH3, 4-Cl, 4-Br, 4-F, 3-Br, 3-CH3) from substituted phenylacetic acids and o-aminobenzenes as the starting materials, and dioxygen as the sole oxidant using inexpensive CuSO4 as the catalyst obtained in moderate to good yields, is reported. The procedure was based on sequential copper-catalyzed decarboxylation and aerobic cyclization reactions. In the experiment, the researchers used many compounds, for example, 2-(3-Bromophenyl)benzo[d]oxazole (cas: 99586-31-9Electric Literature of C13H8BrNO).
2-(3-Bromophenyl)benzo[d]oxazole (cas: 99586-31-9) belongs to benzoxazole derivatives. Benzoxazole derivatives have different biological activities. Due to its versatile biological properties, benzoxazole has been incorporated as an essential pharmacophore and substructure in many medicinal compounds.Electric Literature of C13H8BrNO
Referemce:
Benzoxazole – Wikipedia,
Benzoxazole | C7H5NO – PubChem