Iodine Promoted One-Pot Synthesis of 2-Aryl Benzoxazoles from Amidoximes via Oxidative Cyclization and Ring Contraction was written by Zhang, Yong;Ji, Min. And the article was included in European Journal of Organic Chemistry in 2019.Recommanded Product: 99586-31-9 This article mentions the following:
A mol. I2-promoted one-pot synthesis of 2-aryl benzoxazoles was developed by using amidoximes rather than the limited 2-aminophenols or 2-haloamides as substrates. The amidoxime substrates provided unique and efficient strategies for converting readily available aniline and benzaldehyde precursors into valuable chems. This transformation proceeded smoothly under transition-metal-free conditions through a sequential oxidative cyclization and ring contraction and provided a potential route for introducing certain groups at any site of the scaffold. In the experiment, the researchers used many compounds, for example, 2-(3-Bromophenyl)benzo[d]oxazole (cas: 99586-31-9Recommanded Product: 99586-31-9).
2-(3-Bromophenyl)benzo[d]oxazole (cas: 99586-31-9) belongs to benzoxazole derivatives. Benzoxazole nucleus is one of the most important heterocyclic compounds exhibiting remarkable pharmacological activities. Benzoxazoles are prominent in medicinal chemistry due to their wide spectrum of pharmacological activities such as antiparkinson, inhibition of hepatitis C virus, 5-HT3 antagonistic effect.Recommanded Product: 99586-31-9
Referemce:
Benzoxazole – Wikipedia,
Benzoxazole | C7H5NO – PubChem