Chemical composition and anti-inflammatory activity of the essential oil of Nigerian Psorospermum tenuifolium (Hook. F.) was written by Zubair, M. F.;Oladosu, I. A.;Olawore, N. O.;Fakunle, C. O.. And the article was included in International Journal of Essential Oil Therapeutics in 2009.Application In Synthesis of 2,5-Dimethylbenzoxazole This article mentions the following:
The chem. composition of the essential oils obtained by hydrodistillation from the leaves and roots of Psorospermum tenuifolium collected from North Central Nigeria were analyzed by GC and GC/MS. Twenty-nine compounds representing 93.54% of the leaf essential oil and thirteen compounds representing 83.63% of the root essential oil were determined The two types of oils were differentiated according to their main components. The major constituents of the leaf oil were linalool, α-terpineol,β-caryophyllene, 3-carene and α-gurjunene. The root oil was predominantly monoterpenes that included α-pinene, β-pinene, limonene and myrcene. The leaf essential oil was subjected to anti-inflammatory assay due to its higher number of compounds At 5.0 and 2.5 mg dose levels, the oil exhibited significant anti-inflammatory activity with an edema reduction of 92.3% and 76.9% resp., which was more effective than that demonstrated by a 0.25 mg dose of indomethacin. In the experiment, the researchers used many compounds, for example, 2,5-Dimethylbenzoxazole (cas: 5676-58-4Application In Synthesis of 2,5-Dimethylbenzoxazole).
2,5-Dimethylbenzoxazole (cas: 5676-58-4) belongs to benzoxazole derivatives. Benzoxazoles belong to the group of well-known antifungal agents with antioxidant, antiallergic, antitumoral and antiparasitic activity. In the past years, numerous benzoxazole derivatives have been synthesised and evaluated for their biological potential.Application In Synthesis of 2,5-Dimethylbenzoxazole
Referemce:
Benzoxazole – Wikipedia,
Benzoxazole | C7H5NO – PubChem